Effexor (Venlafaxine) Extended Release Withdrawal can manifest as any of the following symptoms:
Effexor Withdrawal SymptomsThere are hundreds, if not thousands, of websites that illuminate the darkside to SSRI discontinuation. Many of which point to Effexor (Venlafaxine) as of the most difficult anti-depressents to decrease dosages in regards to withdrawal symptoms. Here are just a few that can help shed some light on your current situation or that of someone you know.
http://www.theroadback.org/effexor.aspx
Venlafaxine[edit]Sudden discontinuation of venlafaxine (brand name Effexor) has a high risk of causing potentially severe withdrawal symptoms. Even missing a single dose can cause symptoms of withdrawal.[30][31] The high risk of withdrawal symptoms reflects venlafaxine’s short half-life as well as its effect as a dual uptake inhibitor.[22] Discontinuations have a tendency to be significantly stronger than the withdrawal effects of other antidepressants including the tricyclic antidepressants, but are similar in nature to those of SSRIs with a short half-life such as paroxetine.
Symptoms of discontinuation are similar to other antidepressants including irritability, restlessness, headache, nausea, fatigue, excessive sweating,dysphoria, tremor, vertigo, irregularities in blood pressure, dizziness, visual and auditory hallucinations, feelings of abdominal distension, andparesthesia. Other non-specific mental symptoms may include impaired concentration, bizarre dreams, delirium, cataplexy, agitation, hostility, and worsening of depressive symptoms. Online help groups consistently mention withdrawal from venlafaxine as triggering dreams of a particularly distressing and hellish quality. Electric shock sensations have also been reported[29][31] with many patients describing the symptoms as “brain zaps”. It has been suggested the sensations may represent an alteration of neuronal activity in the central nervous system.[36]
(Ref: http://en.wikipedia.org/wiki/SSRI_discontinuation_syndrome )
http://www.theroadback.org describes Effexor withdrawal as…
Effexor withdrawal - Anorexia – No longer having a desire to eat.
Effexor withdrawal - Apothous Stomatitis – Painful red and swollen open sores on a mucus membrane of the mouth commonly called a canker sore.
Effexor withdrawal - Ataxia – Loss of the ability to move the body with coordination.
Effexor withdrawal - Arterial Fibrillation – A condition of abnormal twitching of the muscles in the blood vessels that moves the oxygenated blood from the heart to the rest of the body. The unusual twitching is rapid and irregular and replaces the normal rhythm of contraction of the muscle, which sometimes causes a lack of circulation and pulse.
Effexor withdrawal - Blood Cholesterol Increased – An abnormal condition where there is a greater amount in the blood of the oily/fatty substances known as cholesterol. Cholesterol is a necessary part of living cells (along with proteins and carbohydrates). Because cholesterol only slightly dissolves in water, it can build up on the walls of the blood vessels, therefore blocking/decreasing the amount of blood flow, which causes blood pressure to go up. If not corrected, this condition is associated with coronary artery disease.
Effexor withdrawal - Blood Creatinine Increased – A greater than normal number of creatinine or muscular chemical waste molecules in the blood. Creatinine plays a major role in energy production in muscles. Since creatinine levels are normally maintained by the kidneys, Blood Creatinine Increased is an indicator of kidney malfunction or failure.
Effexor withdrawal - Blood in Stool – The blood that is in your bowel movement usually comes from any place along your digestive tract (from your mouth to your anus). The stool can appear black and foul-smelling (usually from the upper part of your digestive tract) or red or maroon-colored (usually from the large intestine area). Hemorrhoids are the usual cause for blood in the bowels.
Effexor withdrawal - Bundle Branch Block Right – These are specialized cells in the upper right heart chamber and are the heart’s pacemaker. They send electrical signals to the heart that keeps it beating or contracting regularly. Normally the signal goes to the lower heart chambers at the same time through the bundle of His (hiss) on both the left and right sides of the heart, so the lower chambers contract at the same time. When the bundle is damaged on the right side, the signal does not fire at the same time as the left, which changes the pace of blood flow. This can lead to a person fainting.
Effexor withdrawal - Cardiac Failure – A heart disorder where the heart does not function as usual and may completely stop working.
Effexor withdrawal - Cardiac Failure Congestive – The body is asking for the heart to supply more blood than it is capable of producing and maintaining. Normally, a body can tolerate an increased amount of work for quite some time. The condition is characterized by weakness, shortness of breath, and a fluid build-up in the body tissues causing swelling.
Effexor withdrawal - Cold Sweat – The skin is clammy and moist and you feel chilled. This is a reaction to a shock or pain as well as to fear and nervousness.
Effexor withdrawal - Colitis – A condition where the large intestine becomes irritated from the use of the drug.
Effexor withdrawal - Coronary Artery Disease – A condition where the blood vessels that mainly carry the blood away from the heart become clogged up or narrowed usually by fatty deposits. The first symptom is pain spreading from the upper left body caused by not enough oxygen reaching the heart.
Effexor withdrawal - Dehydration – An extreme loss of water from the body or the organs of the body as in sickness or not drinking enough fluids.
Effexor withdrawal - Diplopia – The condition where a person is looking at one object and instead of normally seeing just the one object he sees two. This is also call double vision.
Effexor withdrawal - Diverticulitis – There are pouches or sacs on the inside of the intestines that look like fingers. This increases the area for the body to absorb nutrients as they pass through the intestines. These sacs become irritated and swollen and end up trapping waste that would normally be eliminated, causing pain and constipation.
Effexor withdrawal - Dysarthria – The inability to control the mouth muscles when forming words so the words are not clearly spoken and heard.
Effexor withdrawal - Dyslipidemia – The normal fat metabolism in the blood is interfered with.
Effexor withdrawal - Dysphagia – Trouble swallowing or the inability to swallow.
Effexor withdrawal - Ecchymosis – When a blood vessel breaks and creates a purple discoloration of the skin.
Effexor withdrawal - Edema – An abnormal build up of excess fluids in the cells, tissues, and the spaces between the tissues creating swelling.
Effexor withdrawal - Edema Peripheral – The abnormal build up of fluids in the tissues of the ankles and legs causing painless swelling in the legs, ankles, and feet. If you squeeze the swollen area it leaves an indentation on the skin for a few minutes.
Effexor withdrawal - Ejaculation Delayed – The man is not able to release sperm either during sexual intercourse or with manual stimulation in the presence of his sexual partner in spite of his wish to do so.
Effexor withdrawal - Ejaculation Dysfunction – A condition where the man has one or more of the following symptoms: He is not able to have an erection, not able to have an orgasm, has a decreased interest in sex, is sexually inhibited, or it is painful to ejaculate sperm.
Effexor withdrawal - Erectile Dysfunction – Incapable of having sexual intercourse. Even though a man desires sex he is inhibited in his sexual activity and is unable to have or maintain an erection of the penis.
Effexor withdrawal - Erythema – a skin redness caused by the swelling with blood of the tiny blood vessels of the skin as in burns.
Effexor withdrawal - Erythematous Rash – Redness of the skin from the swelling of the tiny blood vessels with skin irritation (itching, burning, tingling, pain) and breakouts (eruptions).
Effexor withdrawal - Esophageal Stenosis Acquired – The tube that moves food from the mouth to the stomach narrows.
Effexor withdrawal - Exfoliative Dermatitis – The unusual and not normal condition of scaling and shedding of the skin cells. The skin is usually red colored.
Effexor withdrawal - Face Edema – The tissues of the face become swollen.
Effexor withdrawal - Feeling Jittery – A physical sensation of nervous unease.
Effexor withdrawal - Gastric Irritation – An inflamed and sore stomach.
Effexor withdrawal - Gastric Ulcer – An open, irritated, and infected sore in the wall of the stomach.
Effexor withdrawal - Gingivitis – Sore, swollen and red gums in the mouth that bleed easily.
Effexor withdrawal - Glaucoma – The delicate nerve to the eye, the optic nerve, becomes easily damaged with the build-up of excess fluid pressure within the eyeball. The first sign of glaucoma is loss of peripheral (side) vision. It can progress to total blindness.
Effexor withdrawal - Hepatic Steatosis – Excessive amounts of fat in the liver.
Effexor withdrawal - Hyperhidrosis – The triggering of an excess of sweat being produced on the soles of the feet, the palms, or the underarms which can cause embarrassment or losing grip on a pen or other items.
Effexor withdrawal - Hyperkeratosis – An abnormal enlargement of the skin tissues causing the skin cells to increase in size.
Effexor withdrawal - Hyperlipidemia – An abnormally high number of fat cells in the blood.
Effexor withdrawal - Hypertriglyceridemia – Too many triglycerides in the blood.
Triglycerides are three fatty acids bound together in one molecule stored by the body and available to create high levels of energy when used.
Effexor withdrawal - Hypoesthesia – A partial loss of sensation or general loss of awareness.
Effexor withdrawal - Impaired Gastric Emptying – The contents of the stomach are not passed into the intestines as normal due to the stomach losing the muscular strength to do so.
Effexor withdrawal - Increased White Blood cell Count – This is an increase in the number of cells in the blood that are responsible for the removal of bacteria and other unwanted particles. They fight disease and infection by enclosing foreign particles and removing them. An example of a disease that would increase white blood cell count would be Leukemia.
Effexor withdrawal - Insomnia – Not able to fall asleep or sleeping for a shorter time than desired, thus not being able to properly rest and feeling un-refreshed. As a result, a person can become irritable, have difficulty concentrating and feel a lack of energy. This can be caused by stimulants such as by caffeine or drugs or by mental anxiety and stress. Mental stress can be communicated and relieved.
Effexor withdrawal - Irritable Bowel Syndrome – A painful condition where either the muscles or the nerves of the lower intestines, are not responding normally. This results in an alternating condition of diarrhea followed by constipation, back and forth.
Effexor withdrawal - Keratoconjunctivitis Sicca – A condition where the outer coating of the eyeball is dry because of a decrease in the normal amount of tears in the eye. As a result, the eyeball and inside of the eyelid thickens and hardens sometimes causing the vision to be less sharp.
Effexor withdrawal - Leukopenia – An unnaturally low number of white blood cells circulating in the blood.
Effexor withdrawal - Loose Stools – The bowel movement is runny instead of formed.
Effexor withdrawal - Lower Abdominal Pain – A hurtful irritation of the nerve endings in the area of the hipbones housing the lower digestive tract. Pain usually means tissue damage.
Effexor withdrawal - Lymphadenopathy – The lymph nodes, where the immune cells are located, become larger than is normal because of a high concentration of white blood cells.
Effexor withdrawal - Macular Degeneration – The gradual loss of central vision, which is the sharpest vision while peripheral eyesight, is unaffected.
Effexor withdrawal - Maculopathy – An abnormal condition of the yellow spot of the eye, which is located in the center of the inner lining of the eyeball and connected to the main nerve to the eye and is responsible for sharp vision.
Effexor withdrawal - Mania – Unusually irrational, excessive and/or exaggerated behavior or moods ranging from enthusiasm, sexuality, gaiety, impulsiveness and irritability to violence.
Effexor withdrawal - Melena – Abnormally darkly colored stools as a result of hemorrhaging in the digestive tract where the blood has interacted with the digestive juices creating the dark color in the bowel movement.
Effexor withdrawal - Micturition Urgency – A sudden desire to urinate usually followed by leakage.
Effexor withdrawal - Mood Swings – An emotional shifting as from a state of happiness to a state of depression for a period of time.
Effexor withdrawal - Myocardial Infarction – The blood going to the heart is delayed or stopped causing middle muscle tissue in the heart wall to die.
Effexor withdrawal - Nasopharyngitis – Irritation, redness and swelling tissues in the nose and the tube leading from the mouth to the voice box as well as the tubes leading to the ears.
Effexor withdrawal - Nephropathy – An abnormally functioning or diseased kidney.
Effexor withdrawal - Nervousness – Jumpy, jittery, anxious, and troubled with an irritable temperament.
Effexor withdrawal - Night Sweats – The water-salt, waste product the skin releases is called sweat or perspiration. With night sweats you become wide awake in the middle of the night shivering and cold and wet with your sheets/pajamas soaked in perspiration making it difficult to go back to sleep.
Effexor withdrawal - Nightmare – Dreams that make you afraid or leave feelings of fear, terror, and upset long after waking up.
Effexor withdrawal - Orgasm Abnormal – Unable to have an orgasm with normal sexual stimulation.
Effexor withdrawal - Oropharyngeal Swelling – A swelling in the area from the soft part of the roof of the mouth to the back of the mouth.
Effexor withdrawal - Pain in Extremity – A painful feeling in the legs, arms, hands, and feet.
Effexor withdrawal - Pharyngolaryngeal Pain – Pain in the area of the respiratory tract (organs of breathing) from the throat to the voice box and above the windpipe.
Effexor withdrawal - Photopsia – A condition where a person see lights, sparks or colors in front of your eyes.
Effexor withdrawal - Photosensitivity Reaction – An exaggerated sunburn reaction that is not normal in proportion to the amount of exposure to the light.
Effexor withdrawal - Pollakiuria – Urinating much more frequently than normal – as often as once every five to fifteen minutes.
Effexor withdrawal - Pressure of Speech – A condition where the individual cannot voice his ideas fast enough with the pressure of there being not enough time to say it.
Effexor withdrawal - Pruritic Rash – Extremely itchy, red, swollen bumps on the skin.
Effexor withdrawal - Pyrexia – Fever or the increase in body temperature that is usually a sign of infection.
Effexor withdrawal - Retinal Detachment – The thin layer lining the back of the eyeball (the retina) detaches from the back of the eyeball. This thin layer is like the film of a camera because it sends the images a person views to the brain. When it detaches it causes a reduced ability to see.
Effexor withdrawal - Rigors – Shivering or shaking of the body as if chilled, preventing normal responses.
Effexor withdrawal - Skin Ulcer – An open sore or infected skin eruption with swelling, redness, pus, and irritation.
Effexor withdrawal - Sleep Disorder – These are a list of sleep disorders such as teeth grinding, insomnia, jet lag, sleep walking, abnormally falling asleep during the middle of a conversation after a full night’s rest, uncontrolled body motions keeping one awake, etc.
Effexor withdrawal - Suicide, Completed – An attack on oneself that is life threatening resulting in death.
Effexor withdrawal - Upper Respiratory Tract Infection – Where the organs of breathing near the mouth such as the nose and sinuses, become infected and are usually treated by antibiotics.
Effexor withdrawal - Urinary Hesitation – Hard to start or hard to continue emptying one’s bladder.
Effexor withdrawal - Urinary Incontinence – Urinating without intending to do so because of a weakening of the muscles in the hip area from the drug affecting the nerves or the drug blocking a persons thinking process.
Effexor withdrawal - Urinary Retention – The inability to completely empty the bladder despite having the urge to do so. This can lead to infections or damage to the urinary organs.
Effexor withdrawal - Urine Flow Decreased – Dehydration of the body causing a lesser flow of urine than normal with the body reabsorbing the waste.
Effexor withdrawal - Urine Output Decreased – A condition where the output of urine produced in a 24-hour period is less than 500 ml.
Effexor withdrawal - Weight Decreased – Unintentional weight loss.
Effexor withdrawal – Weight Increased – An unusual, usually rapid weight increase.
Clinical Studies
Association between CYP2C19 polymorphism and depressive symptoms.
Sim SC, Nordin L, Andersson TM, Virding S, Olsson M, Pedersen NL, Ingelman-Sundberg M.
Am J Med Genet B Neuropsychiatr Genet. 2010 Apr 7. [Epub ahead of print]Effexor: 20468063 [Effexor - as supplied by publisher]Related Effexor Citations
[Diagnosis of epilepsy complicated by panic disorder and a non-specific reaction to a ssri.]
Wanders AJ, de Leeuw AS, van Megen HJ.
Tijdschr Psychiatr. 2010;52(5):349-52. Dutch. Effexor: 20458682 [Effexor - in process]Free Effexor ArticleRelated Effexor Citations
Influence of citalopram on interdigestive gastrointestinal motility in man.
Janssen P, Vos R, Tack J.
Aliment Pharmacol Ther. 2010 May 8. [Epub ahead of print]Effexor: 20456311 [Effexor - as supplied by publisher]Related Effexor Citations
A randomized controlled trial of antidepressant continuation for major depression following traumatic brain injury.
Rapoport MJ, Mitchell RA, McCullagh S, Herrmann N, Chan F, Kiss A, Feinstein A, Lanctôt KL.
J Clin Psychiatry. 2010 Apr 20. [Epub ahead of print]Effexor: 20441723 [Effexor - as supplied by publisher]Related Effexor Citations
Variation in the risk of suicide attempts and completed suicides by antidepressant agent in adults: a propensity score-adjusted analysis of 9 years’ data.
Schneeweiss S, Patrick AR, Solomon DH, Mehta J, Dormuth C, Miller M, Lee JC, Wang PS.
Arch Gen Psychiatry. 2010 May;67(5):497-506.Effexor: 20439831 [Effexor - indexed for MEDLINE]Related Effexor Citations
Toxicity of antidepressants: rates of suicide relative to prescribing and non-fatal overdose.
Hawton K, Bergen H, Simkin S, Cooper J, Waters K, Gunnell D, Kapur N.
Br J Psychiatry. 2010 May;196(5):354-8.Effexor: 20435959 [Effexor - in process]Related Effexor Citations
Medial prefrontal cortex activity during memory encoding of pictures and its relation to symptomatic improvement after citalopram treatment in patients with major depression.
Roy M, Harvey PO, Berlim MT, Mamdani F, Beaulieu MM, Turecki G, Lepage M.
J Psychiatry Neurosci. 2010 May;35(3):152-62.Effexor: 20420766 [Effexor - in process]Free PMC ArticleFree textRelated Effexor Citations
Differential effects of serotonergic and noradrenergic antidepressants on brain activity during a cognitive control task and neurofunctional prediction of treatment outcome in patients with depression.
Wagner G, Koch K, Schachtzabel C, Sobanski T, Reichenbach JR, Sauer H, Schlösser RG.
J Psychiatry Neurosci. 2010 May 1. doi: 10.1503/jpn.090081. [Epub ahead of print]Effexor: 20420762 [Effexor - as supplied by publisher]Free Effexor ArticleRelated Effexor Citations
NEUROENDOCRINE EFFECTS OF CITALOPRAM, A SELECTIVE SEROTONIN RE-UPTAKE INHIBITOR, DURING LIFESPAN IN HUMANS.
Berardelli R, Margarito E, Ghiggia F, Picu A, Balbo M, Bonelli L, Giordano R, Karamouzis I, Bo M, Ghigo E, Arvat E.
J Endocrinol Invest. 2010 Apr 22. [Epub ahead of print]Effexor: 20414043 [Effexor - as supplied by publisher]Related Effexor Citations
Nationwide drug-dispensing data reveal important differences in adherence to drug label recommendations on CYP2D6-dependent drug interactions.
Mannheimer B, Wettermark B, Lundberg M, Pettersson H, von Bahr C, Eliasson E.
Br J Clin Pharmacol. 2010 Apr;69(4):411-7.Effexor: 20406225 [Effexor - in process]Related Effexor Citations
The effect of the NMDA receptor antagonist dizocilpine on behavioral manifestations of serotonin and adrenergic antidepressants in rats.
Pruus K, Rudissaar R, Allikmets L, Harro J.
Methods Find Exp Clin Pharmacol. 2010 Mar;32(2):123-8.Effexor: 20401349 [Effexor - in process]Related Effexor Citations
The role of the serotoninergic system in the regulation of thyroid function in old rats.
Masalova OO, Sapronov NS.
Bull Exp Biol Med. 2009 Nov;148(5):815-8.Effexor: 20396800 [Effexor - in process]Related Effexor Citations
Antidepressant-Induced Sexual Dysfunction among Newer Antidepressants in a Naturalistic Setting.
Lee KU, Lee YM, Nam JM, Lee HK, Kweon YS, Lee CT, Jun TY.
Psychiatry Investig. 2010 Mar;7(1):55-9. Epub 2010 Feb 8.Effexor: 20396434 [Effexor - in process]Free PMC ArticleFree textRelated Effexor Citations
Comparative safety of antidepressant agents for children and adolescents regarding suicidal acts.
Schneeweiss S, Patrick AR, Solomon DH, Dormuth CR, Miller M, Mehta J, Lee JC, Wang PS.
Pediatrics. 2010 May;125(5):876-88. Epub 2010 Apr 12.Effexor: 20385637 [Effexor - indexed for MEDLINE]Related Effexor Citations
Citalopram (antidepressant) administration causes sexual dysfunction in male mice through RF-amide related peptide in the dorsomedial hypothalamus.
Soga T, Wong DW, Clarke IJ, Parhar IS.
Neuropharmacology. 2010 Apr 8. [Epub ahead of print]Effexor: 20381503 [Effexor - as supplied by publisher]Related Effexor Citations
Prescription patterns of antidepressants: findings from a US claims database.
Milea D, Verpillat P, Guelfucci F, Toumi M, Lamure M.
Curr Med Res Opin. 2010 Jun;26(6):1343-53.Effexor: 20373875 [Effexor - in process]Related Effexor Citations
Aripiprazole Improves Depressive Symptoms and Immunological Response to Antiretroviral Therapy in an HIV-Infected Subject with Resistant Depression.
Cecchelli C, Grassi G, Pallanti S.
Case Report Med. 2010;2010:836214. Epub 2010 Mar 30.Effexor: 20369069 [Effexor - in process]Free PMC ArticleFree textRelated Effexor Citations
Association of polymorphisms in genes regulating the corticotropin-releasing factor system with antidepressant treatment response.
Binder EB, Owens MJ, Liu W, Deveau TC, Rush AJ, Trivedi MH, Fava M, Bradley B, Ressler KJ, Nemeroff CB.
Arch Gen Psychiatry. 2010 Apr;67(4):369-79.Effexor: 20368512 [Effexor - indexed for MEDLINE]Related Effexor Citations
High rates of sustained virological response in hepatitis C virus-infected injection drug users receiving directly observed therapy with peginterferon alpha-2a (40KD) (PEGASYS) and once-daily ribavirin.
Waizmann M, Ackermann G.
J Subst Abuse Treat. 2010 Jun;38(4):338-45. Epub 2010 Apr 1.Effexor: 20362408 [Effexor - in process]Related Effexor Citations
Multi-residue analysis of pharmaceutical compounds in wastewaters by dual solid-phase microextraction coupled to liquid chromatography electrospray ionization ion trap mass spectrometry.
Unceta N, Sampedro MC, Abu Bakar NK, Gómez-Caballero A, Goicolea MA, Barrio RJ.
J Chromatogr A. 2010 May 14;1217(20):3392-9. Epub 2010 Mar 15.Effexor: 20362295 [Effexor - in process]Related Effexor Citations
Augmentation with citalopram for suicidal ideation in middle-aged and older outpatients with schizophrenia and schizoaffective disorder who have subthreshold depressive symptoms: a randomized controlled trial.
Zisook S, Kasckow JW, Lanouette NM, Golshan S, Fellows I, Vahia I, Mohamed S, Rao S.
J Clin Psychiatry. 2010 Mar 9. [Epub ahead of print]Effexor: 20361918 [Effexor - as supplied by publisher]Related Effexor Citations
Genome-wide pharmacogenetics of antidepressant response in the GENDEP project.
Uher R, Perroud N, Ng MY, Hauser J, Henigsberg N, Maier W, Mors O, Placentino A, Rietschel M, Souery D, Zagar T, Czerski PM, Jerman B, Larsen ER, Schulze TG, Zobel A, Cohen-Woods S, Pirlo K, Butler AW, Muglia P, Barnes MR, Lathrop M, Farmer A, Breen G, Aitchison KJ, Craig I, Lewis CM, McGuffin P.
Am J Psychiatry. 2010 May;167(5):555-64. Epub 2010 Apr 1.Effexor: 20360315 [Effexor - indexed for MEDLINE]Related Effexor Citations
Subtype-selective nicotinic acetylcholine receptor agonists enhance the responsiveness to citalopram and reboxetine in the mouse forced swim test.
Andreasen JT, Nielsen EO, Christensen JK, Olsen GM, Peters D, Mirza NR, Redrobe JP.
J Psychopharmacol. 2010 Apr 1. [Epub ahead of print]Effexor: 20360159 [Effexor - as supplied by publisher]Related Effexor Citations
A highly sensitive LC-MS/MS method for the determination of S-citalopram in rat plasma: application to a pharmacokinetic study in rats.
Suresh PS, Giri S, Husain R, Mullangi R.
Biomed Chromatogr. 2010 Mar 29. [Epub ahead of print]Effexor: 20352615 [Effexor - as supplied by publisher]Related Effexor Citations
Psychostimulant-like discriminative stimulus and locomotor sensitization properties of the wake-promoting agent modafinil in rodents.
Paterson NE, Fedolak A, Olivier B, Hanania T, Ghavami A, Caldarone B.
Pharmacol Biochem Behav. 2010 Jun;95(4):449-56. Epub 2010 Mar 25.Effexor: 20346966 [Effexor - in process]Related Effexor Citations
Efficacy and safety of escitalopram versus citalopram in major depressive disorder: a 6-week, multicenter, randomized, double-blind, flexible-dose study.
Ou JJ, Xun GL, Wu RR, Li LH, Fang MS, Zhang HG, Xie SP, Shi JG, Du B, Yuan XQ, Zhao JP.
Psychopharmacology (Berl). 2010 Mar 26. [Epub ahead of print]Effexor: 20340011 [Effexor - as supplied by publisher]Related Effexor Citations
Removal of pharmaceutical and personal care products (PPCPs) under nitrifying and denitrifying conditions.
Suarez S, Lema JM, Omil F.
Water Res. 2010 May;44(10):3214-24. Epub 2010 Mar 6.Effexor: 20338614 [Effexor - in process]Related Effexor Citations
Glycogen: a novel branched polysaccharide chiral selector in CE.
Chen J, Du Y, Zhu F, Chen B.
Electrophoresis. 2010 Mar;31(6):1044-50.Effexor: 20309915 [Effexor - in process]Related Effexor Citations
Human lymphoblastoid cell line panels: novel tools for assessing shared drug pathways.
Morag A, Kirchheiner J, Rehavi M, Gurwitz D.
Pharmacogenomics. 2010 Mar;11(3):327-40.Effexor: 20235789 [Effexor - in process]Related Effexor Citations
Open channel block of Kv1.5 currents by citalopram.
Lee HM, Hahn SJ, Choi BH.
Acta Pharmacol Sin. 2010 Apr;31(4):429-35. Epub 2010 Mar 15.Effexor: 20228830 [Effexor - in process]Related Effexor Citations
Are typical starting doses of the selective serotonin reuptake inhibitors sub-optimal? A meta-analysis of randomized, double-blind, placebo-controlled, dose-finding studies in major depressive disorder.
Papakostas GI, Charles D, Fava M.
World J Biol Psychiatry. 2010 Mar;11(2 Pt 2):300-7.Effexor: 20218793 [Effexor - in process]Related Effexor Citations
Melatonin inhibits serotonin transporter activity in intestinal epithelial cells.
Matheus N, Mendoza C, Iceta R, Mesonero JE, Alcalde AI.
J Pineal Res. 2010 May;48(4):332-9. Epub 2010 Mar 4.Effexor: 20210852 [Effexor - in process]Related Effexor Citations
Salvage use of citalopram for treatment of fluoxetine-resistant premature ejaculation in recently married men: a prospective clinical trial.
Dadfar MR, Baghinia MR.
Urol J. 2010 Winter;7(1):40-4.Effexor: 20209455 [Effexor - in process]Free Effexor ArticleRelated Effexor Citations
[Citalopram hepatotoxicity.]
Rubio Merino MI, Arranz Carrero A, Alvarez García JF, Antón Martínez J.
Med Clin (Barc). 2010 Mar 4. [Epub ahead of print] Spanish. No abstract available. Effexor: 20206946 [Effexor - as supplied by publisher]Related Effexor Citations
[Depression]
Mischo M, Nigg C, Kiss A.
Praxis (Bern 1994). 2010 Mar 3;99(5):271-6; quiz 277-8. Review. German. No abstract available. Effexor: 20205083 [Effexor - indexed for MEDLINE]Related Effexor Citations
Aripiprazole as adjunct to a mood stabilizer and citalopram in bipolar depression: a randomized placebo-controlled pilot study.
Quante A, Zeugmann S, Luborzewski A, Schommer N, Langosch J, Born C, Anghelescu I, Wolf J.
Hum Psychopharmacol. 2010 Mar;25(2):126-32.Effexor: 20196183 [Effexor - in process]Related Effexor Citations
Validity of the Definite and Semidefinite Questionnaire version of the Hamilton Depression Scale, the Hamilton Subscale and the Melancholia Scale. Part I.
Bent-Hansen J, Bech P.
Eur Arch Psychiatry Clin Neurosci. 2010 Mar 2. [Epub ahead of print]Effexor: 20195869 [Effexor - as supplied by publisher]Related Effexor Citations
Increases in serotonergic neuronal activity following intracerebroventricular administration of AF64A in rats.
Park SH, Lim DK.
Arch Pharm Res. 2010 Feb;33(2):301-8. Epub 2010 Feb 24.Effexor: 20195832 [Effexor - in process]Related Effexor Citations
Citalopram enhances cocaine’s subjective effects in rats.
Soto PL, Hiranita T, Katz JL.
Behav Pharmacol. 2009 Dec;20(8):759-62.Effexor: 20195220 [Effexor - in process]Related Effexor Citations
Association of mu-opioid receptor variants and response to citalopram treatment in major depressive disorder.
Garriock HA, Tanowitz M, Kraft JB, Dang VC, Peters EJ, Jenkins GD, Reinalda MS, McGrath PJ, von Zastrow M, Slager SL, Hamilton SP.
Am J Psychiatry. 2010 May;167(5):565-73. Epub 2010 Mar 1.Effexor: 20194481 [Effexor - indexed for MEDLINE]Related Effexor Citations
Pharmacologically induced/exacerbated restless legs syndrome, periodic limb movements of sleep, and REM behavior disorder/REM sleep without atonia: literature review, qualitative scoring, and comparative analysis.
Hoque R, Chesson AL Jr.
J Clin Sleep Med. 2010 Feb 15;6(1):79-83. Review.Effexor: 20191944 [Effexor - indexed for MEDLINE]Related Effexor Citations
Sex differences in the serotonergic influence on the hypothalamic-pituitary-adrenal stress axis.
Goel N, Bale TL.
Endocrinology. 2010 Apr;151(4):1784-94. Epub 2010 Feb 25.Effexor: 20185764 [Effexor - indexed for MEDLINE]Related Effexor Citations
Efficacy and tolerability of antidepressants for treatment of depression in coronary artery disease: a meta-analysis.
Dowlati Y, Herrmann N, Swardfager WL, Reim EK, Lanctôt KL.
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fMRI tracks reductions in repetitive behaviors in autism: Two case studies.
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Deaths involving serotonergic drugs.
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Breast cancer recurrence risk related to concurrent use of SSRI antidepressants and tamoxifen.
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Baseline neurocognitive profiles differentiate abstainers and non-abstainers in a cocaine clinical trial.
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Clinical trials in CNS–SMi’s eighth annual conference.
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Jiang T, Rong Z, Peng L, Chen B, Xie Y, Chen C, Sun J, Xu Y, Lu Y, Chen H.
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In response to van Gorp F. et al. Escitalopram overdose.
Lugassy DM, Hoffman RS, Chessex N.
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Serotonin modulates sensitivity to reward and negative feedback in a probabilistic reversal learning task in rats.
Bari A, Theobald DE, Caprioli D, Mar AC, Aidoo-Micah A, Dalley JW, Robbins TW.
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Heffner JL, Tran GQ, Johnson CS, Barrett SW, Blom TJ, Thompson RD, Anthenelli RM.
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[Discontinuation of antidepressant serotonergic antidepressant]
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Improving depression and enhancing resilience in family dementia caregivers: a pilot randomized placebo-controlled trial of escitalopram.
Lavretsky H, Siddarth P, Irwin MR.
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Antidepressant medication and executive dysfunction: a deleterious interaction in late-life depression.
Sneed JR, Culang ME, Keilp JG, Rutherford BR, Devanand DP, Roose SP.
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Treatment with an SSRI antidepressant restores hippocampo-hypothalamic corticosteroid feedback and reverses insulin resistance in low-birth-weight rats.
Buhl ES, Jensen TK, Jessen N, Elfving B, Buhl CS, Kristiansen SB, Pold R, Solskov L, Schmitz O, Wegener G, Lund S, Petersen KF.
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The 5-HT(7) receptor as a mediator and modulator of antidepressant-like behavior.
Sarkisyan G, Roberts AJ, Hedlund PB.
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Brain imaging of serotonin 4 receptors in humans with [11C]SB207145-PET.
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Serotonergic neurons mediate ectopic release of dopamine induced by L-DOPA in a rat model of Parkinson’s disease.
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http://www.theroadback.org/effexor.aspx
Venlafaxine[edit]Sudden discontinuation of venlafaxine (brand name Effexor) has a high risk of causing potentially severe withdrawal symptoms. Even missing a single dose can cause symptoms of withdrawal.[30][31] The high risk of withdrawal symptoms reflects venlafaxine’s short half-life as well as its effect as a dual uptake inhibitor.[22] Discontinuations have a tendency to be significantly stronger than the withdrawal effects of other antidepressants including the tricyclic antidepressants, but are similar in nature to those of SSRIs with a short half-life such as paroxetine.
Symptoms of discontinuation are similar to other antidepressants including irritability, restlessness, headache, nausea, fatigue, excessive sweating,dysphoria, tremor, vertigo, irregularities in blood pressure, dizziness, visual and auditory hallucinations, feelings of abdominal distension, andparesthesia. Other non-specific mental symptoms may include impaired concentration, bizarre dreams, delirium, cataplexy, agitation, hostility, and worsening of depressive symptoms. Online help groups consistently mention withdrawal from venlafaxine as triggering dreams of a particularly distressing and hellish quality. Electric shock sensations have also been reported[29][31] with many patients describing the symptoms as “brain zaps”. It has been suggested the sensations may represent an alteration of neuronal activity in the central nervous system.[36]
(Ref: http://en.wikipedia.org/wiki/SSRI_discontinuation_syndrome )
http://www.theroadback.org describes Effexor withdrawal as…
Effexor withdrawal - Anorexia – No longer having a desire to eat.
Effexor withdrawal - Apothous Stomatitis – Painful red and swollen open sores on a mucus membrane of the mouth commonly called a canker sore.
Effexor withdrawal - Ataxia – Loss of the ability to move the body with coordination.
Effexor withdrawal - Arterial Fibrillation – A condition of abnormal twitching of the muscles in the blood vessels that moves the oxygenated blood from the heart to the rest of the body. The unusual twitching is rapid and irregular and replaces the normal rhythm of contraction of the muscle, which sometimes causes a lack of circulation and pulse.
Effexor withdrawal - Blood Cholesterol Increased – An abnormal condition where there is a greater amount in the blood of the oily/fatty substances known as cholesterol. Cholesterol is a necessary part of living cells (along with proteins and carbohydrates). Because cholesterol only slightly dissolves in water, it can build up on the walls of the blood vessels, therefore blocking/decreasing the amount of blood flow, which causes blood pressure to go up. If not corrected, this condition is associated with coronary artery disease.
Effexor withdrawal - Blood Creatinine Increased – A greater than normal number of creatinine or muscular chemical waste molecules in the blood. Creatinine plays a major role in energy production in muscles. Since creatinine levels are normally maintained by the kidneys, Blood Creatinine Increased is an indicator of kidney malfunction or failure.
Effexor withdrawal - Blood in Stool – The blood that is in your bowel movement usually comes from any place along your digestive tract (from your mouth to your anus). The stool can appear black and foul-smelling (usually from the upper part of your digestive tract) or red or maroon-colored (usually from the large intestine area). Hemorrhoids are the usual cause for blood in the bowels.
Effexor withdrawal - Bundle Branch Block Right – These are specialized cells in the upper right heart chamber and are the heart’s pacemaker. They send electrical signals to the heart that keeps it beating or contracting regularly. Normally the signal goes to the lower heart chambers at the same time through the bundle of His (hiss) on both the left and right sides of the heart, so the lower chambers contract at the same time. When the bundle is damaged on the right side, the signal does not fire at the same time as the left, which changes the pace of blood flow. This can lead to a person fainting.
Effexor withdrawal - Cardiac Failure – A heart disorder where the heart does not function as usual and may completely stop working.
Effexor withdrawal - Cardiac Failure Congestive – The body is asking for the heart to supply more blood than it is capable of producing and maintaining. Normally, a body can tolerate an increased amount of work for quite some time. The condition is characterized by weakness, shortness of breath, and a fluid build-up in the body tissues causing swelling.
Effexor withdrawal - Cold Sweat – The skin is clammy and moist and you feel chilled. This is a reaction to a shock or pain as well as to fear and nervousness.
Effexor withdrawal - Colitis – A condition where the large intestine becomes irritated from the use of the drug.
Effexor withdrawal - Coronary Artery Disease – A condition where the blood vessels that mainly carry the blood away from the heart become clogged up or narrowed usually by fatty deposits. The first symptom is pain spreading from the upper left body caused by not enough oxygen reaching the heart.
Effexor withdrawal - Dehydration – An extreme loss of water from the body or the organs of the body as in sickness or not drinking enough fluids.
Effexor withdrawal - Diplopia – The condition where a person is looking at one object and instead of normally seeing just the one object he sees two. This is also call double vision.
Effexor withdrawal - Diverticulitis – There are pouches or sacs on the inside of the intestines that look like fingers. This increases the area for the body to absorb nutrients as they pass through the intestines. These sacs become irritated and swollen and end up trapping waste that would normally be eliminated, causing pain and constipation.
Effexor withdrawal - Dysarthria – The inability to control the mouth muscles when forming words so the words are not clearly spoken and heard.
Effexor withdrawal - Dyslipidemia – The normal fat metabolism in the blood is interfered with.
Effexor withdrawal - Dysphagia – Trouble swallowing or the inability to swallow.
Effexor withdrawal - Ecchymosis – When a blood vessel breaks and creates a purple discoloration of the skin.
Effexor withdrawal - Edema – An abnormal build up of excess fluids in the cells, tissues, and the spaces between the tissues creating swelling.
Effexor withdrawal - Edema Peripheral – The abnormal build up of fluids in the tissues of the ankles and legs causing painless swelling in the legs, ankles, and feet. If you squeeze the swollen area it leaves an indentation on the skin for a few minutes.
Effexor withdrawal - Ejaculation Delayed – The man is not able to release sperm either during sexual intercourse or with manual stimulation in the presence of his sexual partner in spite of his wish to do so.
Effexor withdrawal - Ejaculation Dysfunction – A condition where the man has one or more of the following symptoms: He is not able to have an erection, not able to have an orgasm, has a decreased interest in sex, is sexually inhibited, or it is painful to ejaculate sperm.
Effexor withdrawal - Erectile Dysfunction – Incapable of having sexual intercourse. Even though a man desires sex he is inhibited in his sexual activity and is unable to have or maintain an erection of the penis.
Effexor withdrawal - Erythema – a skin redness caused by the swelling with blood of the tiny blood vessels of the skin as in burns.
Effexor withdrawal - Erythematous Rash – Redness of the skin from the swelling of the tiny blood vessels with skin irritation (itching, burning, tingling, pain) and breakouts (eruptions).
Effexor withdrawal - Esophageal Stenosis Acquired – The tube that moves food from the mouth to the stomach narrows.
Effexor withdrawal - Exfoliative Dermatitis – The unusual and not normal condition of scaling and shedding of the skin cells. The skin is usually red colored.
Effexor withdrawal - Face Edema – The tissues of the face become swollen.
Effexor withdrawal - Feeling Jittery – A physical sensation of nervous unease.
Effexor withdrawal - Gastric Irritation – An inflamed and sore stomach.
Effexor withdrawal - Gastric Ulcer – An open, irritated, and infected sore in the wall of the stomach.
Effexor withdrawal - Gingivitis – Sore, swollen and red gums in the mouth that bleed easily.
Effexor withdrawal - Glaucoma – The delicate nerve to the eye, the optic nerve, becomes easily damaged with the build-up of excess fluid pressure within the eyeball. The first sign of glaucoma is loss of peripheral (side) vision. It can progress to total blindness.
Effexor withdrawal - Hepatic Steatosis – Excessive amounts of fat in the liver.
Effexor withdrawal - Hyperhidrosis – The triggering of an excess of sweat being produced on the soles of the feet, the palms, or the underarms which can cause embarrassment or losing grip on a pen or other items.
Effexor withdrawal - Hyperkeratosis – An abnormal enlargement of the skin tissues causing the skin cells to increase in size.
Effexor withdrawal - Hyperlipidemia – An abnormally high number of fat cells in the blood.
Effexor withdrawal - Hypertriglyceridemia – Too many triglycerides in the blood.
Triglycerides are three fatty acids bound together in one molecule stored by the body and available to create high levels of energy when used.
Effexor withdrawal - Hypoesthesia – A partial loss of sensation or general loss of awareness.
Effexor withdrawal - Impaired Gastric Emptying – The contents of the stomach are not passed into the intestines as normal due to the stomach losing the muscular strength to do so.
Effexor withdrawal - Increased White Blood cell Count – This is an increase in the number of cells in the blood that are responsible for the removal of bacteria and other unwanted particles. They fight disease and infection by enclosing foreign particles and removing them. An example of a disease that would increase white blood cell count would be Leukemia.
Effexor withdrawal - Insomnia – Not able to fall asleep or sleeping for a shorter time than desired, thus not being able to properly rest and feeling un-refreshed. As a result, a person can become irritable, have difficulty concentrating and feel a lack of energy. This can be caused by stimulants such as by caffeine or drugs or by mental anxiety and stress. Mental stress can be communicated and relieved.
Effexor withdrawal - Irritable Bowel Syndrome – A painful condition where either the muscles or the nerves of the lower intestines, are not responding normally. This results in an alternating condition of diarrhea followed by constipation, back and forth.
Effexor withdrawal - Keratoconjunctivitis Sicca – A condition where the outer coating of the eyeball is dry because of a decrease in the normal amount of tears in the eye. As a result, the eyeball and inside of the eyelid thickens and hardens sometimes causing the vision to be less sharp.
Effexor withdrawal - Leukopenia – An unnaturally low number of white blood cells circulating in the blood.
Effexor withdrawal - Loose Stools – The bowel movement is runny instead of formed.
Effexor withdrawal - Lower Abdominal Pain – A hurtful irritation of the nerve endings in the area of the hipbones housing the lower digestive tract. Pain usually means tissue damage.
Effexor withdrawal - Lymphadenopathy – The lymph nodes, where the immune cells are located, become larger than is normal because of a high concentration of white blood cells.
Effexor withdrawal - Macular Degeneration – The gradual loss of central vision, which is the sharpest vision while peripheral eyesight, is unaffected.
Effexor withdrawal - Maculopathy – An abnormal condition of the yellow spot of the eye, which is located in the center of the inner lining of the eyeball and connected to the main nerve to the eye and is responsible for sharp vision.
Effexor withdrawal - Mania – Unusually irrational, excessive and/or exaggerated behavior or moods ranging from enthusiasm, sexuality, gaiety, impulsiveness and irritability to violence.
Effexor withdrawal - Melena – Abnormally darkly colored stools as a result of hemorrhaging in the digestive tract where the blood has interacted with the digestive juices creating the dark color in the bowel movement.
Effexor withdrawal - Micturition Urgency – A sudden desire to urinate usually followed by leakage.
Effexor withdrawal - Mood Swings – An emotional shifting as from a state of happiness to a state of depression for a period of time.
Effexor withdrawal - Myocardial Infarction – The blood going to the heart is delayed or stopped causing middle muscle tissue in the heart wall to die.
Effexor withdrawal - Nasopharyngitis – Irritation, redness and swelling tissues in the nose and the tube leading from the mouth to the voice box as well as the tubes leading to the ears.
Effexor withdrawal - Nephropathy – An abnormally functioning or diseased kidney.
Effexor withdrawal - Nervousness – Jumpy, jittery, anxious, and troubled with an irritable temperament.
Effexor withdrawal - Night Sweats – The water-salt, waste product the skin releases is called sweat or perspiration. With night sweats you become wide awake in the middle of the night shivering and cold and wet with your sheets/pajamas soaked in perspiration making it difficult to go back to sleep.
Effexor withdrawal - Nightmare – Dreams that make you afraid or leave feelings of fear, terror, and upset long after waking up.
Effexor withdrawal - Orgasm Abnormal – Unable to have an orgasm with normal sexual stimulation.
Effexor withdrawal - Oropharyngeal Swelling – A swelling in the area from the soft part of the roof of the mouth to the back of the mouth.
Effexor withdrawal - Pain in Extremity – A painful feeling in the legs, arms, hands, and feet.
Effexor withdrawal - Pharyngolaryngeal Pain – Pain in the area of the respiratory tract (organs of breathing) from the throat to the voice box and above the windpipe.
Effexor withdrawal - Photopsia – A condition where a person see lights, sparks or colors in front of your eyes.
Effexor withdrawal - Photosensitivity Reaction – An exaggerated sunburn reaction that is not normal in proportion to the amount of exposure to the light.
Effexor withdrawal - Pollakiuria – Urinating much more frequently than normal – as often as once every five to fifteen minutes.
Effexor withdrawal - Pressure of Speech – A condition where the individual cannot voice his ideas fast enough with the pressure of there being not enough time to say it.
Effexor withdrawal - Pruritic Rash – Extremely itchy, red, swollen bumps on the skin.
Effexor withdrawal - Pyrexia – Fever or the increase in body temperature that is usually a sign of infection.
Effexor withdrawal - Retinal Detachment – The thin layer lining the back of the eyeball (the retina) detaches from the back of the eyeball. This thin layer is like the film of a camera because it sends the images a person views to the brain. When it detaches it causes a reduced ability to see.
Effexor withdrawal - Rigors – Shivering or shaking of the body as if chilled, preventing normal responses.
Effexor withdrawal - Skin Ulcer – An open sore or infected skin eruption with swelling, redness, pus, and irritation.
Effexor withdrawal - Sleep Disorder – These are a list of sleep disorders such as teeth grinding, insomnia, jet lag, sleep walking, abnormally falling asleep during the middle of a conversation after a full night’s rest, uncontrolled body motions keeping one awake, etc.
Effexor withdrawal - Suicide, Completed – An attack on oneself that is life threatening resulting in death.
Effexor withdrawal - Upper Respiratory Tract Infection – Where the organs of breathing near the mouth such as the nose and sinuses, become infected and are usually treated by antibiotics.
Effexor withdrawal - Urinary Hesitation – Hard to start or hard to continue emptying one’s bladder.
Effexor withdrawal - Urinary Incontinence – Urinating without intending to do so because of a weakening of the muscles in the hip area from the drug affecting the nerves or the drug blocking a persons thinking process.
Effexor withdrawal - Urinary Retention – The inability to completely empty the bladder despite having the urge to do so. This can lead to infections or damage to the urinary organs.
Effexor withdrawal - Urine Flow Decreased – Dehydration of the body causing a lesser flow of urine than normal with the body reabsorbing the waste.
Effexor withdrawal - Urine Output Decreased – A condition where the output of urine produced in a 24-hour period is less than 500 ml.
Effexor withdrawal - Weight Decreased – Unintentional weight loss.
Effexor withdrawal – Weight Increased – An unusual, usually rapid weight increase.
Clinical Studies
Association between CYP2C19 polymorphism and depressive symptoms.
Sim SC, Nordin L, Andersson TM, Virding S, Olsson M, Pedersen NL, Ingelman-Sundberg M.
Am J Med Genet B Neuropsychiatr Genet. 2010 Apr 7. [Epub ahead of print]Effexor: 20468063 [Effexor - as supplied by publisher]Related Effexor Citations
[Diagnosis of epilepsy complicated by panic disorder and a non-specific reaction to a ssri.]
Wanders AJ, de Leeuw AS, van Megen HJ.
Tijdschr Psychiatr. 2010;52(5):349-52. Dutch. Effexor: 20458682 [Effexor - in process]Free Effexor ArticleRelated Effexor Citations
Influence of citalopram on interdigestive gastrointestinal motility in man.
Janssen P, Vos R, Tack J.
Aliment Pharmacol Ther. 2010 May 8. [Epub ahead of print]Effexor: 20456311 [Effexor - as supplied by publisher]Related Effexor Citations
A randomized controlled trial of antidepressant continuation for major depression following traumatic brain injury.
Rapoport MJ, Mitchell RA, McCullagh S, Herrmann N, Chan F, Kiss A, Feinstein A, Lanctôt KL.
J Clin Psychiatry. 2010 Apr 20. [Epub ahead of print]Effexor: 20441723 [Effexor - as supplied by publisher]Related Effexor Citations
Variation in the risk of suicide attempts and completed suicides by antidepressant agent in adults: a propensity score-adjusted analysis of 9 years’ data.
Schneeweiss S, Patrick AR, Solomon DH, Mehta J, Dormuth C, Miller M, Lee JC, Wang PS.
Arch Gen Psychiatry. 2010 May;67(5):497-506.Effexor: 20439831 [Effexor - indexed for MEDLINE]Related Effexor Citations
Toxicity of antidepressants: rates of suicide relative to prescribing and non-fatal overdose.
Hawton K, Bergen H, Simkin S, Cooper J, Waters K, Gunnell D, Kapur N.
Br J Psychiatry. 2010 May;196(5):354-8.Effexor: 20435959 [Effexor - in process]Related Effexor Citations
Medial prefrontal cortex activity during memory encoding of pictures and its relation to symptomatic improvement after citalopram treatment in patients with major depression.
Roy M, Harvey PO, Berlim MT, Mamdani F, Beaulieu MM, Turecki G, Lepage M.
J Psychiatry Neurosci. 2010 May;35(3):152-62.Effexor: 20420766 [Effexor - in process]Free PMC ArticleFree textRelated Effexor Citations
Differential effects of serotonergic and noradrenergic antidepressants on brain activity during a cognitive control task and neurofunctional prediction of treatment outcome in patients with depression.
Wagner G, Koch K, Schachtzabel C, Sobanski T, Reichenbach JR, Sauer H, Schlösser RG.
J Psychiatry Neurosci. 2010 May 1. doi: 10.1503/jpn.090081. [Epub ahead of print]Effexor: 20420762 [Effexor - as supplied by publisher]Free Effexor ArticleRelated Effexor Citations
NEUROENDOCRINE EFFECTS OF CITALOPRAM, A SELECTIVE SEROTONIN RE-UPTAKE INHIBITOR, DURING LIFESPAN IN HUMANS.
Berardelli R, Margarito E, Ghiggia F, Picu A, Balbo M, Bonelli L, Giordano R, Karamouzis I, Bo M, Ghigo E, Arvat E.
J Endocrinol Invest. 2010 Apr 22. [Epub ahead of print]Effexor: 20414043 [Effexor - as supplied by publisher]Related Effexor Citations
Nationwide drug-dispensing data reveal important differences in adherence to drug label recommendations on CYP2D6-dependent drug interactions.
Mannheimer B, Wettermark B, Lundberg M, Pettersson H, von Bahr C, Eliasson E.
Br J Clin Pharmacol. 2010 Apr;69(4):411-7.Effexor: 20406225 [Effexor - in process]Related Effexor Citations
The effect of the NMDA receptor antagonist dizocilpine on behavioral manifestations of serotonin and adrenergic antidepressants in rats.
Pruus K, Rudissaar R, Allikmets L, Harro J.
Methods Find Exp Clin Pharmacol. 2010 Mar;32(2):123-8.Effexor: 20401349 [Effexor - in process]Related Effexor Citations
The role of the serotoninergic system in the regulation of thyroid function in old rats.
Masalova OO, Sapronov NS.
Bull Exp Biol Med. 2009 Nov;148(5):815-8.Effexor: 20396800 [Effexor - in process]Related Effexor Citations
Antidepressant-Induced Sexual Dysfunction among Newer Antidepressants in a Naturalistic Setting.
Lee KU, Lee YM, Nam JM, Lee HK, Kweon YS, Lee CT, Jun TY.
Psychiatry Investig. 2010 Mar;7(1):55-9. Epub 2010 Feb 8.Effexor: 20396434 [Effexor - in process]Free PMC ArticleFree textRelated Effexor Citations
Comparative safety of antidepressant agents for children and adolescents regarding suicidal acts.
Schneeweiss S, Patrick AR, Solomon DH, Dormuth CR, Miller M, Mehta J, Lee JC, Wang PS.
Pediatrics. 2010 May;125(5):876-88. Epub 2010 Apr 12.Effexor: 20385637 [Effexor - indexed for MEDLINE]Related Effexor Citations
Citalopram (antidepressant) administration causes sexual dysfunction in male mice through RF-amide related peptide in the dorsomedial hypothalamus.
Soga T, Wong DW, Clarke IJ, Parhar IS.
Neuropharmacology. 2010 Apr 8. [Epub ahead of print]Effexor: 20381503 [Effexor - as supplied by publisher]Related Effexor Citations
Prescription patterns of antidepressants: findings from a US claims database.
Milea D, Verpillat P, Guelfucci F, Toumi M, Lamure M.
Curr Med Res Opin. 2010 Jun;26(6):1343-53.Effexor: 20373875 [Effexor - in process]Related Effexor Citations
Aripiprazole Improves Depressive Symptoms and Immunological Response to Antiretroviral Therapy in an HIV-Infected Subject with Resistant Depression.
Cecchelli C, Grassi G, Pallanti S.
Case Report Med. 2010;2010:836214. Epub 2010 Mar 30.Effexor: 20369069 [Effexor - in process]Free PMC ArticleFree textRelated Effexor Citations
Association of polymorphisms in genes regulating the corticotropin-releasing factor system with antidepressant treatment response.
Binder EB, Owens MJ, Liu W, Deveau TC, Rush AJ, Trivedi MH, Fava M, Bradley B, Ressler KJ, Nemeroff CB.
Arch Gen Psychiatry. 2010 Apr;67(4):369-79.Effexor: 20368512 [Effexor - indexed for MEDLINE]Related Effexor Citations
High rates of sustained virological response in hepatitis C virus-infected injection drug users receiving directly observed therapy with peginterferon alpha-2a (40KD) (PEGASYS) and once-daily ribavirin.
Waizmann M, Ackermann G.
J Subst Abuse Treat. 2010 Jun;38(4):338-45. Epub 2010 Apr 1.Effexor: 20362408 [Effexor - in process]Related Effexor Citations
Multi-residue analysis of pharmaceutical compounds in wastewaters by dual solid-phase microextraction coupled to liquid chromatography electrospray ionization ion trap mass spectrometry.
Unceta N, Sampedro MC, Abu Bakar NK, Gómez-Caballero A, Goicolea MA, Barrio RJ.
J Chromatogr A. 2010 May 14;1217(20):3392-9. Epub 2010 Mar 15.Effexor: 20362295 [Effexor - in process]Related Effexor Citations
Augmentation with citalopram for suicidal ideation in middle-aged and older outpatients with schizophrenia and schizoaffective disorder who have subthreshold depressive symptoms: a randomized controlled trial.
Zisook S, Kasckow JW, Lanouette NM, Golshan S, Fellows I, Vahia I, Mohamed S, Rao S.
J Clin Psychiatry. 2010 Mar 9. [Epub ahead of print]Effexor: 20361918 [Effexor - as supplied by publisher]Related Effexor Citations
Genome-wide pharmacogenetics of antidepressant response in the GENDEP project.
Uher R, Perroud N, Ng MY, Hauser J, Henigsberg N, Maier W, Mors O, Placentino A, Rietschel M, Souery D, Zagar T, Czerski PM, Jerman B, Larsen ER, Schulze TG, Zobel A, Cohen-Woods S, Pirlo K, Butler AW, Muglia P, Barnes MR, Lathrop M, Farmer A, Breen G, Aitchison KJ, Craig I, Lewis CM, McGuffin P.
Am J Psychiatry. 2010 May;167(5):555-64. Epub 2010 Apr 1.Effexor: 20360315 [Effexor - indexed for MEDLINE]Related Effexor Citations
Subtype-selective nicotinic acetylcholine receptor agonists enhance the responsiveness to citalopram and reboxetine in the mouse forced swim test.
Andreasen JT, Nielsen EO, Christensen JK, Olsen GM, Peters D, Mirza NR, Redrobe JP.
J Psychopharmacol. 2010 Apr 1. [Epub ahead of print]Effexor: 20360159 [Effexor - as supplied by publisher]Related Effexor Citations
A highly sensitive LC-MS/MS method for the determination of S-citalopram in rat plasma: application to a pharmacokinetic study in rats.
Suresh PS, Giri S, Husain R, Mullangi R.
Biomed Chromatogr. 2010 Mar 29. [Epub ahead of print]Effexor: 20352615 [Effexor - as supplied by publisher]Related Effexor Citations
Psychostimulant-like discriminative stimulus and locomotor sensitization properties of the wake-promoting agent modafinil in rodents.
Paterson NE, Fedolak A, Olivier B, Hanania T, Ghavami A, Caldarone B.
Pharmacol Biochem Behav. 2010 Jun;95(4):449-56. Epub 2010 Mar 25.Effexor: 20346966 [Effexor - in process]Related Effexor Citations
Efficacy and safety of escitalopram versus citalopram in major depressive disorder: a 6-week, multicenter, randomized, double-blind, flexible-dose study.
Ou JJ, Xun GL, Wu RR, Li LH, Fang MS, Zhang HG, Xie SP, Shi JG, Du B, Yuan XQ, Zhao JP.
Psychopharmacology (Berl). 2010 Mar 26. [Epub ahead of print]Effexor: 20340011 [Effexor - as supplied by publisher]Related Effexor Citations
Removal of pharmaceutical and personal care products (PPCPs) under nitrifying and denitrifying conditions.
Suarez S, Lema JM, Omil F.
Water Res. 2010 May;44(10):3214-24. Epub 2010 Mar 6.Effexor: 20338614 [Effexor - in process]Related Effexor Citations
Glycogen: a novel branched polysaccharide chiral selector in CE.
Chen J, Du Y, Zhu F, Chen B.
Electrophoresis. 2010 Mar;31(6):1044-50.Effexor: 20309915 [Effexor - in process]Related Effexor Citations
Human lymphoblastoid cell line panels: novel tools for assessing shared drug pathways.
Morag A, Kirchheiner J, Rehavi M, Gurwitz D.
Pharmacogenomics. 2010 Mar;11(3):327-40.Effexor: 20235789 [Effexor - in process]Related Effexor Citations
Open channel block of Kv1.5 currents by citalopram.
Lee HM, Hahn SJ, Choi BH.
Acta Pharmacol Sin. 2010 Apr;31(4):429-35. Epub 2010 Mar 15.Effexor: 20228830 [Effexor - in process]Related Effexor Citations
Are typical starting doses of the selective serotonin reuptake inhibitors sub-optimal? A meta-analysis of randomized, double-blind, placebo-controlled, dose-finding studies in major depressive disorder.
Papakostas GI, Charles D, Fava M.
World J Biol Psychiatry. 2010 Mar;11(2 Pt 2):300-7.Effexor: 20218793 [Effexor - in process]Related Effexor Citations
Melatonin inhibits serotonin transporter activity in intestinal epithelial cells.
Matheus N, Mendoza C, Iceta R, Mesonero JE, Alcalde AI.
J Pineal Res. 2010 May;48(4):332-9. Epub 2010 Mar 4.Effexor: 20210852 [Effexor - in process]Related Effexor Citations
Salvage use of citalopram for treatment of fluoxetine-resistant premature ejaculation in recently married men: a prospective clinical trial.
Dadfar MR, Baghinia MR.
Urol J. 2010 Winter;7(1):40-4.Effexor: 20209455 [Effexor - in process]Free Effexor ArticleRelated Effexor Citations
[Citalopram hepatotoxicity.]
Rubio Merino MI, Arranz Carrero A, Alvarez García JF, Antón Martínez J.
Med Clin (Barc). 2010 Mar 4. [Epub ahead of print] Spanish. No abstract available. Effexor: 20206946 [Effexor - as supplied by publisher]Related Effexor Citations
[Depression]
Mischo M, Nigg C, Kiss A.
Praxis (Bern 1994). 2010 Mar 3;99(5):271-6; quiz 277-8. Review. German. No abstract available. Effexor: 20205083 [Effexor - indexed for MEDLINE]Related Effexor Citations
Aripiprazole as adjunct to a mood stabilizer and citalopram in bipolar depression: a randomized placebo-controlled pilot study.
Quante A, Zeugmann S, Luborzewski A, Schommer N, Langosch J, Born C, Anghelescu I, Wolf J.
Hum Psychopharmacol. 2010 Mar;25(2):126-32.Effexor: 20196183 [Effexor - in process]Related Effexor Citations
Validity of the Definite and Semidefinite Questionnaire version of the Hamilton Depression Scale, the Hamilton Subscale and the Melancholia Scale. Part I.
Bent-Hansen J, Bech P.
Eur Arch Psychiatry Clin Neurosci. 2010 Mar 2. [Epub ahead of print]Effexor: 20195869 [Effexor - as supplied by publisher]Related Effexor Citations
Increases in serotonergic neuronal activity following intracerebroventricular administration of AF64A in rats.
Park SH, Lim DK.
Arch Pharm Res. 2010 Feb;33(2):301-8. Epub 2010 Feb 24.Effexor: 20195832 [Effexor - in process]Related Effexor Citations
Citalopram enhances cocaine’s subjective effects in rats.
Soto PL, Hiranita T, Katz JL.
Behav Pharmacol. 2009 Dec;20(8):759-62.Effexor: 20195220 [Effexor - in process]Related Effexor Citations
Association of mu-opioid receptor variants and response to citalopram treatment in major depressive disorder.
Garriock HA, Tanowitz M, Kraft JB, Dang VC, Peters EJ, Jenkins GD, Reinalda MS, McGrath PJ, von Zastrow M, Slager SL, Hamilton SP.
Am J Psychiatry. 2010 May;167(5):565-73. Epub 2010 Mar 1.Effexor: 20194481 [Effexor - indexed for MEDLINE]Related Effexor Citations
Pharmacologically induced/exacerbated restless legs syndrome, periodic limb movements of sleep, and REM behavior disorder/REM sleep without atonia: literature review, qualitative scoring, and comparative analysis.
Hoque R, Chesson AL Jr.
J Clin Sleep Med. 2010 Feb 15;6(1):79-83. Review.Effexor: 20191944 [Effexor - indexed for MEDLINE]Related Effexor Citations
Sex differences in the serotonergic influence on the hypothalamic-pituitary-adrenal stress axis.
Goel N, Bale TL.
Endocrinology. 2010 Apr;151(4):1784-94. Epub 2010 Feb 25.Effexor: 20185764 [Effexor - indexed for MEDLINE]Related Effexor Citations
Efficacy and tolerability of antidepressants for treatment of depression in coronary artery disease: a meta-analysis.
Dowlati Y, Herrmann N, Swardfager WL, Reim EK, Lanctôt KL.
Can J Psychiatry. 2010 Feb;55(2):91-9.Effexor: 20181304 [Effexor - in process]Related Effexor Citations
Impact and clinical management of depression in patients with coronary artery disease.
Summers KM, Martin KE, Watson K.
Pharmacotherapy. 2010 Mar;30(3):304-22.Effexor: 20180613 [Effexor - in process]Related Effexor Citations
fMRI tracks reductions in repetitive behaviors in autism: Two case studies.
Dichter GS, Sikich L, Mahorney S, Felder JN, Lam KS, Turner-Brown L, Bodfish J.
Neurocase. 2010 Feb 22:1-10. [Epub ahead of print]Effexor: 20178033 [Effexor - as supplied by publisher]Related Effexor Citations
Deaths involving serotonergic drugs.
Pilgrim JL, Gerostamoulos D, Drummer OH.
Forensic Sci Int. 2010 May 20;198(1-3):110-7. Epub 2010 Feb 20.Effexor: 20172668 [Effexor - in process]Related Effexor Citations
Inhibitory and facilitory actions of isocyanine derivatives at human and rat organic cation transporters 1, 2 and 3: a comparison to human alpha1- and alpha2-adrenoceptor subtypes.
Amphoux A, Millan MJ, Cordi A, Bönisch H, Vialou V, Mannoury la Cour C, Dupuis DS, Giros B, Gautron S.
Eur J Pharmacol. 2010 May 25;634(1-3):1-9. Epub 2010 Feb 17.Effexor: 20170649 [Effexor - in process]Related Effexor Citations
Escitalopram causes fewer seizures in human overdose than citalopram.
Yilmaz Z, Ceschi A, Rauber-Lüthy C, Sauer O, Stedtler U, Prasa D, Seidel C, Hackl E, Hoffmann-Walbeck P, Gerber-Zupan G, Bauer K, Kupferschmidt H, Kullak-Ublick GA, Wilks M.
Clin Toxicol (Phila). 2010 Mar;48(3):207-12.Effexor: 20170390 [Effexor - indexed for MEDLINE]Related Effexor Citations
Repeated intermittent methylenedioxymethamphetamine exposure protects against the behavioral and neurotoxic, but not hyperthermic, effects of an MDMA binge in adult rats.
Piper BJ, Ali SF, Daniels LG, Meyer JS.
Synapse. 2010 Jun;64(6):421-31.Effexor: 20169574 [Effexor - in process]Related Effexor Citations
Antidepressant drugs for chronic urological pelvic pain: an evidence-based review.
Papandreou C, Skapinakis P, Giannakis D, Sofikitis N, Mavreas V.
Adv Urol. 2009;2009:797031. Epub 2010 Feb 14.Effexor: 20169141 [Effexor - in process]Free PMC ArticleFree textRelated Effexor Citations
Selective serotonin reuptake inhibitors potentiate the rapid antidepressant-like effects of serotonin4 receptor agonists in the rat.
Lucas G, Du J, Romeas T, Mnie-Filali O, Haddjeri N, Piñeyro G, Debonnel G.
PLoS One. 2010 Feb 16;5(2):e9253.Effexor: 20169084 [Effexor - in process]Free PMC ArticleFree textRelated Effexor Citations
Estradiol valerate elicits antidepressant-like effects in middle-aged female rats under chronic mild stress.
Romano-Torres M, Fernández-Guasti A.
Behav Pharmacol. 2010 Mar;21(2):104-11.Effexor: 20168212 [Effexor - in process]Related Effexor Citations
Anxiolytic-like property of risperidone and olanzapine as examined in multiple measures of fear in rats.
Sun T, He W, Hu G, Li M.
Pharmacol Biochem Behav. 2010 May;95(3):298-307. Epub 2010 Feb 16.Effexor: 20167232 [Effexor - in process]Related Effexor Citations
Citalopram not effective for repetitive behaviour in autistic spectrum disorders.
Myers SM.
Evid Based Ment Health. 2010 Feb;13(1):22. No abstract available. Effexor: 20164519 [Effexor]Related Effexor Citations
Is escitalopram really relevantly superior to citalopram in treatment of major depressive disorder? A meta-analysis of head-to-head randomized trials.
Trkulja V.
Croat Med J. 2010 Feb;51(1):61-73.Effexor: 20162747 [Effexor - in process]Free PMC ArticleFree textRelated Effexor Citations
Transmembrane domain 6 of the human serotonin transporter contributes to an aqueously accessible binding pocket for serotonin and the psychostimulant 3,4-methylene dioxymethamphetamine.
Field JR, Henry LK, Blakely RD.
J Biol Chem. 2010 Apr 9;285(15):11270-80. Epub 2010 Feb 16.Effexor: 20159976 [Effexor - indexed for MEDLINE]Related Effexor Citations
Prinzmetal-variant angina in a patient using zolmitriptan and citalopram.
Acikel S, Dogan M, Sari M, Kilic H, Akdemir R.
Am J Emerg Med. 2010 Feb;28(2):257.e3-6.Effexor: 20159412 [Effexor - indexed for MEDLINE]Related Effexor Citations
[Personality test and prediction of antidepressive treatment effect in mental illness]
Thorleifsson A, Holst K, Diaz M, Folker H.
Ugeskr Laeger. 2010 Feb 15;172(7):539-44. Danish. Effexor: 20156404 [Effexor - indexed for MEDLINE]Related Effexor Citations
Breast cancer recurrence risk related to concurrent use of SSRI antidepressants and tamoxifen.
Lash TL, Cronin-Fenton D, Ahern TP, Rosenberg CL, Lunetta KL, Silliman RA, Hamilton-Dutoit S, Garne JP, Ewertz M, Sørensen HT, Pedersen L.
Acta Oncol. 2010 Apr;49(3):305-12.Effexor: 20156115 [Effexor - in process]Related Effexor Citations
Baseline neurocognitive profiles differentiate abstainers and non-abstainers in a cocaine clinical trial.
Schmitz JM, Mooney ME, Green CE, Lane SD, Steinberg JL, Swann AC, Moeller FG.
J Addict Dis. 2009 Jul;28(3):250-7.Effexor: 20155594 [Effexor - in process]Related Effexor Citations
A cognitive deficit induced in rats by chronic intermittent cold stress is reversed by chronic antidepressant treatment.
Danet M, Lapiz-Bluhm S, Morilak DA.
Int J Neuropsychopharmacol. 2010 Feb 11:1-13. [Epub ahead of print]Effexor: 20149267 [Effexor - as supplied by publisher]Related Effexor Citations
Escitalopram–translating molecular properties into clinical benefit: reviewing the evidence in major depression.
Leonard B, Taylor D.
J Psychopharmacol. 2010 Mar 16. [Epub ahead of print]Effexor: 20147575 [Effexor - as supplied by publisher]Related Effexor Citations
A STUDY OF CENTRAL SEROTONINERGIC ACTIVITY IN HEALTHY SUBJECTS AND PATIENTS WITH TYPE 2 DIABETES TREATED BY TRADITIONAL ONE-TOONE CARE OR GROUP CARE.
Trento M, Kucich C, Tibaldi P, Borgo E, Gennari S, Tedesco S, Balbo M, Arvat E, Cavallo F, Ghigo E, Porta M.
J Endocrinol Invest. 2010 Feb 5. [Epub ahead of print]Effexor: 20142635 [Effexor - as supplied by publisher]Related Effexor Citations
Serotonin modulates glutamatergic transmission in the rat olfactory tubercle.
Hadley JK, Halliwell JV.
Eur J Neurosci. 2010 Feb;31(4):659-72. Epub 2010 Feb 5.Effexor: 20141530 [Effexor - in process]Related Effexor Citations
The relationship between antidepressant use and smoking cessation in pregnant women in treatment for substance abuse.
Chisolm MS, Brigham EP, Tuten M, Strain EC, Jones HE.
Am J Drug Alcohol Abuse. 2010 Jan;36(1):46-51.Effexor: 20141396 [Effexor - indexed for MEDLINE]Related Effexor Citations
Use of venlafaxine compared with other antidepressants and the risk of sudden cardiac death or near death: a nested case-control study.
Martinez C, Assimes TL, Mines D, Dell’aniello S, Suissa S.
BMJ. 2010 Feb 5;340:c249. doi: 10.1136/bmj.c249.Effexor: 20139216 [Effexor - indexed for MEDLINE]Free PMC ArticleFree textRelated Effexor Citations
Antidepressants in functional dyspepsia.
Talley NJ, Herrick L, Locke GR.
Expert Rev Gastroenterol Hepatol. 2010 Feb;4(1):5-8. No abstract available. Effexor: 20136584 [Effexor - indexed for MEDLINE]Free Effexor ArticleRelated Effexor Citations
Evaluation of the enantioseparation capability of the novel chiral selector clindamycin phosphate towards basic drugs by micellar electrokinetic chromatography.
Chen B, Du Y.
J Chromatogr A. 2010 Mar 12;1217(11):1806-12. Epub 2010 Jan 21.Effexor: 20132938 [Effexor - indexed for MEDLINE]Related Effexor Citations
Fluoxetine and citalopram exhibit potent antiinflammatory activity in human and murine models of rheumatoid arthritis and inhibit toll-like receptors.
Sacre S, Medghalchi M, Gregory B, Brennan F, Williams R.
Arthritis Rheum. 2010 Mar;62(3):683-93.Effexor: 20131240 [Effexor - indexed for MEDLINE]Related Effexor Citations
Clinical trials in CNS–SMi’s eighth annual conference.
Kirk R.
IDrugs. 2010 Feb;13(2):66-9.Effexor: 20127552 [Effexor - indexed for MEDLINE]Related Effexor Citations
Escitalopram and enhancement of cognitive recovery following stroke.
Jorge RE, Acion L, Moser D, Adams HP Jr, Robinson RG.
Arch Gen Psychiatry. 2010 Feb;67(2):187-96.Effexor: 20124118 [Effexor - indexed for MEDLINE]Related Effexor Citations
Aging impairs the antidepressant-like response to citalopram in male rats.
Herrera-Pérez JJ, Martínez-Mota L, Fernández-Guasti A.
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A common mechanism of action of the selective serotonin reuptake inhibitors citalopram and fluoxetine: reversal of chronic psychosocial stress-induced increase in CRE/CREB-directed gene transcription in transgenic reporter gene mice.
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Antidepressant pharmaceuticals in two U.S. effluent-impacted streams: occurrence and fate in water and sediment, and selective uptake in fish neural tissue.
Schultz MM, Furlong ET, Kolpin DW, Werner SL, Schoenfuss HL, Barber LB, Blazer VS, Norris DO, Vajda AM.
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Simultaneous determination of citalopram and its metabolite in human plasma by LC-MS/MS applied to pharmacokinetic study.
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In response to van Gorp F. et al. Escitalopram overdose.
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The impact of diabetes on depression treatment outcomes.
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Serotonin modulates sensitivity to reward and negative feedback in a probabilistic reversal learning task in rats.
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Combining motivational interviewing with compliance enhancement therapy (MI-CET): development and preliminary evaluation of a new, manual-guided psychosocial adjunct to alcohol-dependence pharmacotherapy.
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Improving depression and enhancing resilience in family dementia caregivers: a pilot randomized placebo-controlled trial of escitalopram.
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Antidepressant medication and executive dysfunction: a deleterious interaction in late-life depression.
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Treatment with an SSRI antidepressant restores hippocampo-hypothalamic corticosteroid feedback and reverses insulin resistance in low-birth-weight rats.
Buhl ES, Jensen TK, Jessen N, Elfving B, Buhl CS, Kristiansen SB, Pold R, Solskov L, Schmitz O, Wegener G, Lund S, Petersen KF.
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The 5-HT(7) receptor as a mediator and modulator of antidepressant-like behavior.
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Brain imaging of serotonin 4 receptors in humans with [11C]SB207145-PET.
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Serotonergic neurons mediate ectopic release of dopamine induced by L-DOPA in a rat model of Parkinson’s disease.
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The B-VITAGE trial: a randomized trial of homocysteine lowering treatment of depression in later life.
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Relationship of residual mood and panic-agoraphobic spectrum phenomenology to quality of life and functional impairment in patients with major depression.
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Changes in 5-HT4 receptor and 5-HT transporter binding in olfactory bulbectomized and glucocorticoid receptor heterozygous mice.
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The identification of inhibitors of Schistosoma mansoni miracidial transformation by incorporating a medium-throughput small-molecule screen.
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Changes in antidepressant metabolism in pregnancy evidenced by metabolic ratios in hair: a novel approach.
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The two enantiomers of citalopram bind to the human serotonin transporter in reversed orientations.
Koldsø H, Severinsen K, Tran TT, Celik L, Jensen HH, Wiborg O, Schiøtt B, Sinning S.
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Diagnostic crossover from obesity to atypical anorexia nervosa – a case report.
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Excessive daytime somnolence in spinocerebellar ataxia type 1.
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Alpha1-adrenoceptors modulate citalopram-induced serotonin release.
Rea K, Folgering J, Westerink BH, Cremers TI.
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Notch1 signaling related hippocampal neurogenesis in adult poststroke depression rats: a valid index for an efficient combined citalopram and WAY100635 pharmacotherapy.
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Diminished neural processing of aversive and rewarding stimuli during selective serotonin reuptake inhibitor treatment.
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